91ºÚÁÏ

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Dr Helen Roberts

DoP Natural Science/Assoc Prof in Skeletal Cancer Research

Helen Roberts
  • School Faculty of Science and Technology

  • Department Natural Sciences

  • Location London

Research activities

Dr Roberts is currently Associate Professor in Skeletal Cancer Research at 91ºÚÁÏ, and coordinates a research track investigating the regulation of primary bone cancer chemoresistance and metastasis.

Grants Awarded

  • Hannah's Willberry Wonder Pony Charity: Suppress-OS: Targeting Osteoclast-Tumour interactions to Suppress Osteosarcoma Metastasis (Principal Investigator; in collaboration with Dr Song Wen, 91ºÚÁÏ and Dr Scott Roberts, Royal Veterinary College, London - £136,000)
  • Hannah's Willberry Wonder Pony Charity: Delineating the metastatic process in osteosarcoma: the role of bone cells, the cell environment and autophagy (Principal Investigator; in collaboration with Dr Scott Roberts, Royal Veterinary College, London - £87,000)
  • PetPlanCharitable Trust: Mechanisms of chemoresistance in canine osteosarcoma (PrincipalInvestigator; 2018; in collaboration with Prof Richard Meeson, Royal VeterinaryCollege, London - £10,000).
  • Bone Cancer Research Trust: ‘MicroRNA regulation ofautophagy-induced chemoresistance in osteosarcoma’ (‘Strictly Research’ AwardWinner; 2017 - £10,000).
  • Research Activities

  • Associate Editor for Frontiers in VeterinaryScience (Oncology in Veterinary Medicine) (2022 – present)
  • Foundingmember of the Primary Bone Cancer Metastasis Network (PBCMetNet; 2019 –present)
  • Memberof the Genomics England Sarcoma Domain Clinical Interpretation Partnership(GeCIP; 2019 – present)
  • ScientificAdvisory Board member for the Osteosarcoma charity 'Willberry's Research' (2016– present)
  • Memberof the Bloomsbury Centre for Skeletal Research (2016 – present)
  • Regularreviewer of scientific manuscripts and grant proposals for funding bodies suchas the Medical Research Council and the Bone Cancer Research Trust.Ìý
  • Publications (Published under ‘Owen HC’ upto 2018)

    Please click here:

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    Current Teaching

    Dr Roberts is Programme Leader for the Faculty of Science and Technology Foundation Programme, overseeing the design, delivery, and quality of teaching that provides students with the core scientific knowledge, academic skills, and support needed to successfully progress into science undergraduate degrees.

    She is also Director of Programmes for Biosciences, providing strategic and academic leadership for bioscience degrees, within the Department of Natural Sciences, overseeing curriculum design, quality assurance, and programme delivery.

    Dr Roberts also contributes to the teaching of oncology, epigenetics, physiology, pharmacology, molecular biology and cell biology on undergraduate and postgraduate modules, and supervises a number of undergraduate (BSc) and postgraduate (MSc, MRes and PhD) research projects.Ìý

    Current Research Students

    PhD: Maria Pop, Wendy Gomez

    MRes:Ìý Iman Majdouli

    Past Research StudentsÌý

    PhD: Kaan Low, Janice Pereira, Daniela Paternina Martinez

    MRes: Gabriel Rosa, Dewa Zazai, Ivan Punev, Charlotte New, Aine Pears, Yathushigan Kulatheepan, Bipusha Tha Shrestha, Akashdeep Ganguly, Eriola Diku


    Biography

    Dr Helen Roberts (nee Owen) gained a PhD from the University of Glasgow whilst based at the Roslin Institute, where she investigated the molecular events surrounding steroid-induced skeletal growth retardation. Following this, Dr Roberts moved to the University of Sheffield where she investigated epigenetic biomarkers which were able to predict cancer progression. She has since coordinated research projects both at KU Leuven in Belgium, where she researched the role of epigenetics and autophagy in critical illness-induced bone loss, and at Barts and the London School of Medicine and Dentistry where she used genome-wide molecular profiling to identify epigenetic biomarkers associated with inflammation and immune suppression in critically ill patients.Ìý

    Dr Roberts is currently Associate Professor in Skeletal Cancer Research at 91ºÚÁÏ, with a research group investigating primary bone cancer metastasis and chemoresistance, the interaction between tumour cells and the bone microenvironment and molecular processes such as autophagy, epigenetics, and microRNA regulation in cancer progression.

    She is also Director of Programmes for Biosciences, providing strategic and academic leadership for bioscience degrees, within the Department of Natural Sciences, overseeing curriculum design, quality assurance, and programme delivery.

    As Foundation Year in Science Programme Lead, she also oversees the design, delivery, and quality of teaching that provides students with the core scientific knowledge, academic skills, and support needed to successfully progress into science undergraduate degrees.

    Qualifications

    Title: Senior Fellow of the Higher Education Academy

    Date: 01 Oct 2022


    Title: PhD

    Notes: The Cellular and Molecular Mechanisms of Glucocorticoid-Induced Growth Retardation

    Date: 01 Oct 2007

    Institution: University of Glasgow and Roslin Institute


    Title: BSc (Hons) Pharmacology with Industrial Experience

    Date: 01 Jun 2003

    Institution: University of Edinburgh


    External activities

  • Associate Editor, Oncology in Veterinary Medicine,
  • Scientific advisory board member, Hannah's Willberry Wonder Pony,
  • Senior Fellow of the Higher Education Academy, Higher Education Academy,
  • Founding Member of the Primary Bone Cancer Metastasis Network (PBCMetNet), Primary Bone Cancer Metastasis Network,
  • Reviewer, Medical Research Council,
  • Publications